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Infection and ResponseFoundationDrug TrialsVaccines

AQA GCSE · Question 01.5 · Infection and Response

When scientists produce a vaccine for a disease the vaccine is tested on live animals.

What is the next stage in testing the vaccine?

Tick (✔) one box.

Answer options:

A.

Testing on cells in a laboratory

B.

Testing on healthy volunteers

C.

Testing on the whole human population

How to approach this question

Recall the stages of drug and vaccine testing. The question states that testing on live animals has already been done. What is the first step in human trials?

Full Answer

B.Testing on healthy volunteers✓ Correct
Testing on healthy volunteers
The development of new drugs and vaccines follows a standard procedure. 1. **Preclinical testing:** Testing on cells, tissues, and computer models in the lab. 2. **Animal testing:** Testing on live animals to see its effect on a whole living organism. 3. **Clinical trials (human testing):** * Phase 1: Testing on a small number of **healthy volunteers** to check for safety and side effects. * Phase 2: Testing on a small number of patients with the disease to check for effectiveness. * Phase 3: Testing on a large number of patients to confirm effectiveness and monitor side effects. The question asks for the stage after animal testing, which is testing on healthy volunteers.

Common mistakes

✗ Getting the order of testing wrong, for example, thinking lab testing comes after animal testing.\n✗ Thinking it goes straight from animals to the whole population.

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