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    PracticeAQA GCSEAQA GCSE Biology Higher Tier Paper 1Question 05.7
    Medium2 marksStructured
    Infection and ResponseHigherdata interpretationdisease interactionmalaria

    AQA GCSE · Question 05.7 · Infection and Response

    Table 4Age in yearsCalculated percentage (%) incidence ofmalaria in children with disorder S2 to < 4694 to < 6636 to < 8508 to 1045> 1073

    Different types of disease may interact. Scientists studied the incidence of malaria infections in children:
    • with disorder S
    • without disorder S.
    The incidence of malaria in children with disorder S was calculated as a percentage of the incidence in children without disorder S. Table 4 shows the results. Describe what the results in Table 4 show about the interaction between disorder S and malaria.

    How to approach this question

    The percentage is for children *with* disorder S compared to children *without* it. If the percentage is 100%, there is no difference. If it's less than 100%, what does that mean for children with disorder S? If it's more than 100%, what does that mean? Describe the overall trend and also look for any changes in the trend as age increases. Use data from the table to support your description.

    Full Answer

    The results show that having disorder S provides some protection against malaria, especially for children aged 8 to 10, where the incidence is lowest (45%). The percentage incidence is below 100% for all age groups up to 10, indicating protection. However, this protective effect seems to decrease in older children (>10 years old), where the incidence rises to 73%.
    The results show an interaction where disorder S appears to offer some protection against malaria. 1. **General Protection:** All the percentage values are below 100%. This means that in every age group studied, children with disorder S had a lower incidence of malaria compared to children without the disorder. This suggests having disorder S is advantageous in areas where malaria is common. 2. **Age-related Trend:** The protective effect is strongest in the 8 to 10 age group, where the incidence of malaria is only 45% of that in children without disorder S. The protection seems to decrease from age 2 up to age 10, but then the incidence rises again for children over 10 (to 73%), suggesting the protective effect may weaken in older children. (This pattern is characteristic of Sickle Cell Anaemia, where being a carrier (heterozygous) provides resistance to malaria).

    Common mistakes

    ✗ Just quoting numbers without explaining what they mean in terms of interaction or protection. ✗ Getting the relationship the wrong way round, e.g., saying disorder S increases the risk of malaria. ✗ Failing to notice the change in the trend for the >10 age group.
    Question 05.6All questionsQuestion 06.1

    Practice the full AQA GCSE Biology Higher Tier Paper 1

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