ExpertAQA GCSE
AQA GCSE Biology Higher Tier Paper 1
52 free questions · No sign-up required to browse
AQA Higher Tier Exam-style past paper with complete mark schemes, hints, AI assistance and detailed explanations.
52
Questions
Hard
Difficulty
60%
Pass mark
Difficulty breakdown
Easy(22)
Medium(26)
Hard(4)
Sample questions
Q01.1Easy1 mark
A root is a plant organ. Plant roots contain many different types of tissue. What is a tissue?
Q01.2Easy1 mark
Tissue in the tip of a plant root contains stem cells. Stem cells can differentiate into any type of cell. Name the type of tissue in plants that contains stem cells.
Q01.3Easy1 mark
In the past many drugs were extracted from plants. Aspirin is a painkiller. Which plant does aspirin originate from?
Q01.4Medium1 mark
Scientists have extracted chemical A from the deadly nightshade plant. Chemical A can be used as a painkiller. Table 1 shows information about where chemical A is found. The scientists usually extract chemical A from the berries of the deadly nightshade plant. Suggest one reason why berries are used instead of leaves or roots.
Q01.5Medium4 marks
A deadly nightshade plant has chlorosis (yellow leaves). The mass of chemical A found in the leaves of the plant is 60% of the mass shown in Table 1. Calculate the mass of chemical A in 200 g of the leaves with chlorosis. Give your answer in mg.
Ready to Practice the full exam?
All 52 questions with worked answers, mark schemes, and AI tutoring.
All questions (52)
Free to browse · no sign-up requiredQ01.1A root is a plant organ. Plant roots contain many different types of tissue. What is a tissue?EasyQ01.2Tissue in the tip of a plant root contains stem cells. Stem cells can differentiate into any type of cell. Name the t...EasyQ01.3In the past many drugs were extracted from plants. Aspirin is a painkiller. Which plant does aspirin originate from?EasyQ01.4Scientists have extracted chemical A from the deadly nightshade plant. Chemical A can be used as a painkiller. Table ...MediumQ01.5A deadly nightshade plant has chlorosis (yellow leaves). The mass of chemical A found in the leaves of the plant is 6...MediumQ01.6Suggest one reason why the leaves of the deadly nightshade plant have chlorosis.EasyQ01.7Chemical A has not been tested in large-scale clinical trials in the UK. It is important for drugs to be tested in cl...EasyQ01.8There are many online reports making claims about the effects of chemical A. Some of these reports are biased. Sugges...EasyQ01.9How can scientists be sure that claims about new drugs are valid?EasyQ02.1This question is about the circulatory system. Figure 1 shows the human heart. Which part of the heart receives oxyge...EasyQ02.2Which part of the heart pumps deoxygenated blood to the lungs?EasyQ02.3A group of cells called the pacemaker controls the resting heart rate. Where in the heart is the pacemaker found?EasyQ02.4Figure 2 shows a cross section of an artery and of a vein. Describe two ways that the structure of an artery is diffe...MediumQ02.5In coronary heart disease, the coronary arteries become narrower. A build-up of fatty material can cause a blockage i...EasyQ02.6Complete Figure 3. You should:
• use a suitable scale for the y-axis
• plot the data from Table 2
• draw a line of be...MediumQ02.7Predict the blood flow in a coronary artery with a 35% blockage. Use Figure 3.EasyQ02.8Explain the effect of a partly blocked coronary artery on the human body.HardQ02.9There are different treatments for a blockage in a coronary artery. Explain how one treatment for a blockage in a cor...MediumQ03.1Salmonella bacteria cause outbreaks of food poisoning in humans. To prevent food poisoning in humans, farmers vaccina...EasyQ03.2During a food poisoning outbreak, scientists identified the farm where the food came from. The farmer had not vaccina...MediumQ03.3Scientists investigated the effectiveness of five different antibiotics on the Salmonella bacteria in the outbreak. A...MediumQ03.4The scientists incubated the bacteria at 37 °C. Students in school laboratories incubate bacteria at 25 °C. Explain w...MediumQ03.5What is the purpose of the paper disc with no antibiotic in Figure 4?EasyQ03.6The scientists concluded that either antibiotic A or antibiotic B should be prescribed to patients with food poisonin...EasyQ03.7The scientists wanted to be more certain about which antibiotic should be prescribed. Describe how the results in Fig...MediumQ03.8One year later, there was another outbreak at the farm involving Salmonella bacteria. Antibiotic B did not have an ef...MediumQ03.9Antibiotics treat food poisoning because they kill Salmonella bacteria inside the human body. Some antibiotics work b...HardQ04.1This question is about exercise. During vigorous exercise, anaerobic respiration occurs in a person's body. Explain t...MediumQ04.2Design an investigation to show the effect of different types of exercise on the heart rate of athletes.HardQ04.3Anabolic steroids are drugs. Anabolic steroids:
• increase muscle mass in humans
• are banned in most competitive spo...MediumQ04.4Scientists use monoclonal antibodies to test for the presence of anabolic steroids in an athlete's urine. To produce ...EasyQ04.5Describe how scientists make monoclonal antibodies using the cell created when a mouse lymphocyte and a tumour cell c...MediumQ04.6What property makes a monoclonal antibody useful in detecting the presence of an anabolic steroid in urine?EasyQ04.7Figure 5 shows a test strip that can detect the presence of an anabolic steroid in an athlete's urine. The end of the...MediumQ04.8Figure 6 shows the urine test results of four athletes. Describe the evidence in Figure 6 that shows the test for ath...MediumQ04.9Which athlete has tested positive for anabolic steroids in their urine?EasyQ05.1The protist that causes malaria is passed from one person to another person by mosquitos. What term describes an orga...EasyQ05.2Figure 7 shows the malarial protist. The malarial protist is a eukaryotic cell. Describe three ways the structure of ...MediumQ05.3During one stage of malaria infection, the malarial protists enter red blood cells and cause them to burst. Explain w...MediumQ05.4The malarial protist reproduces sexually and asexually during a life cycle. Complete Table 3 to give three difference...MediumQ05.5One drug for treating malaria prevents mitosis occurring in the malarial protist. The drug stops the synthesis of new...MediumQ05.6Describe the process of cell division by mitosis.MediumQ05.7Different types of disease may interact. Scientists studied the incidence of malaria infections in children:
• with d...MediumQ06.1This question is about photosynthesis. Complete the symbol equation for photosynthesis.
6 ______ + 6 ______ → C₆H₁₂O₆...EasyQ06.2Figure 8 shows how the rate of photosynthesis changes with light intensity. Which part of the graph could be represen...MediumQ06.3A student investigated the effect of colour of light on the rate of photosynthesis in leaves. Figure 9 shows how the ...EasyQ06.4Give the independent variable and the dependent variable in this investigation.EasyQ06.5All of the air had to be removed from the leaf discs before placing them in the beaker. Suggest one reason why.MediumQ06.6The leaf discs were placed in a beaker of sodium hydrogencarbonate (NaHCO₃) solution. Explain why sodium hydrogencarb...MediumQ06.7Explain why the leaf discs moved to the surface of the solution during the investigation.MediumQ06.8There are two types of chlorophyll in leaves. Figure 10 shows the percentage of different wavelengths of light that t...MediumQ06.9Table 5 is repeated below. The leaf discs in the investigation are green. Explain the results in Table 5 for blue lig...Hard