Describe how scientists make monoclonal antibodies using the cell created when a mouse lymphocyte and a tumour cell combine.

After a hybridoma cell is successfully created, the process continues as follows: 1. **Selection and Cloning:** The hybridoma cells are separated and cultured individually. Each one is tested to find a cell that produces the desired antibody. Once the correct hybridoma cell is identified, it is selected and cloned. Cloning means it is allowed to divide by mitosis many times to produce a large population of genetically identical cells. 2. **Large-scale Production:** This large population of cloned hybridoma cells is then cultured in a fermenter (a large container with controlled conditions and nutrients). 3. **Collection and Purification:** As the cells grow and divide in the culture, they all produce and secrete the exact same type of antibody into the surrounding medium. These monoclonal antibodies are then separated from the culture medium, collected, and purified for use.