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Infection and ResponseHighermonoclonal antibodiesspecificityantigens

AQA GCSE · Question 04.6 · Infection and Response

What property makes a monoclonal antibody useful in detecting the presence of an anabolic steroid in urine?

Answer options:

A.

A monoclonal antibody is quick and easy to produce.

B.

A monoclonal antibody is specific to only one person's urine.

C.

A monoclonal antibody only binds to the anabolic steroid.

D.

A monoclonal antibody can identify many different drugs at the same time.

How to approach this question

Think about the fundamental property of any antibody. They have a specific shape that allows them to bind to one, and only one, type of antigen. How does this relate to detecting a specific drug?

Full Answer

C.A monoclonal antibody only binds to the anabolic steroid.✓ Correct
A monoclonal antibody only binds to the anabolic steroid.
The most important property of monoclonal antibodies for use in diagnostics and testing is their **specificity**. An antibody has a unique, three-dimensional binding site that is complementary in shape to a specific part of a molecule, called an antigen. In this case, the monoclonal antibodies are designed to have a binding site that is complementary only to the anabolic steroid molecule. This means they will bind to the steroid and nothing else in the urine. This high specificity prevents the test from reacting to other hormones or chemicals, ensuring an accurate result and avoiding false positives.

Common mistakes

✗ Confusing specificity with speed or ease of production. ✗ Thinking the antibody is specific to the person rather than the chemical.

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